i used to take Wellbutrin and it worked great for my depression and for smoking. but i broke out in hives. i lowered my dose and i could tell that it increased my acne. i hate to say this but it is the Wellbutrin. i cut out soda and chocolate and tried new acne medication, but that didn't help really. also, Wellbutrin made my skin always feel itchy. it sucks cuz if you give it awhile that stuff really works.