I have been on every acne medication you can think of including accutane. I started using Ortho-Tricyclen with me regime but I continued to have massive breakouts on my cheeks and forehead a week before my period. My gyno then suggested Yasmin since it was Monophasil instead of Triphasil. I've been on Yasmin for two weeks and have already noticed that my skin is drier and has a healthier complexion. My shedding has also reduced from an average of 100+ hairs to 60 hairs. I'm really happy with Yasmin (so far)! Good Luck!