I am on 100mg of Zoloft a day for anxiety and depression. I don' think it helps AT ALL. I am also on Trileptal and Seroquel. What I am is an addict and the only thing I like is mind/mood altering substances, though. I hate the Zoloft for the sexual side effects. My neighbor is on Paxil and it is basically the same thing as Zoloft. She needs it and it helps her. She took it all throughout her pregnancy and it was safe. I don't consider her a pill popper, I consider it taking care of herself. I consider myself a pill popper. Do what is healthy for you after asking your doctor, it would NOT be considered pill popping to take your Zoloft. Jennier