1. You cannot get Flovent or Advair (or even Serevent) in nebulized solution.
2. You CAN get combivent and ventolin in nebulized solution.
3. You CAN get Intal in nebulized solution. Intal is best taken more often than twice a day. Try spacing your puffs of Intal out, 2 puffs every 4 hours or something. What does your dr. think? On a neb this might be tougher to do, though.
4. You CAN get an inhaled steroid in nebulized solution -- down side is that it looks like you're going to be switching to Pulmicort if you go to neb.
5. When you switch to neb, because neb dosages and MDI dosages are different, make sure they keep an eye on your theophylline levels for the first little while to make sure they don't fluctuate.
THe hormones is a good thing to look into. Congrats on paying so much attention! [img]http://www.healthboards.com/ubb/biggrin.gif[/img]
First: I love you ALL for replying. Can't thank you enough.
Now: Wrin: No, I don't do daily peak flows because with me, they are not predictive. I do have a meter, thogh. The PF can be great at 9:00 p.m. and at 4:00 a.m., I'm grabbing for the albuterol. What is ventolin? What is pulmicort? Rescue or long-lasting meds? Steroids or not steroids? The intal, 4 puffs morning and evening, is what the doctor prescribed. I hear you about medicating per the printed label, but that would be hard to do with my work schedule and distance from a place to rinse my mouth. Perhaps that's why he prescribed the twice-per-day regimen. What is pulmicort? Steroid or no? Does it have another name? Thanks for the heads-up on the theophylline levels. I saw that in the literature. Overall, my doctors say the manufacturers are covering their behinds with a lot of the cautionary info they hand out, but I'm included to think we have to be more proactive than they are.
All: So the nebs are used for both fast-acting meds (albuterol) and the longer, maintenance acting meds (Advair, Intal, etc.). I thought it was used solely for rescue med purposes.
Carolyn B: drat on the nausea thing. I want some damn relief from being sick for as many as three days per week each week! Yes, I am complaining.
Charleyhorse: what is atrovent? Isn't that combivent with another name?
Lyn HW: Yup. Guess it is harder for postmenopausals. Wouldn't you think all these highly educated types, and especially my allergist who is postmenopausal, would know about this hormone thing?
Cripes.
I'll be back. I'm having trouble getting the hormones reordered since I went off. I will let you know how this works out.
Ventolin is the brand name for Albuterol. I think they call it something like Proventil in the States? All over the world it's Ventolin/Salbutamol, and only in the USA is it Proventil/Albuterol. Silly kittens.
Pulmicort is an inhaled corticosteroid, sort of like Flovent, but a little different. I found I couldn't tolerate Flovent, so I'm on Pulmicort. Some people found they couldn't tolerate Pulmicort, so they're on Flovent. Flovent works a little FASTER, but neither one works really "better" than the other. Pulmicort is more classically prescribed for little ones because ... well, it's FDA approved for munchkin-type-sized people, and because it's the only corticosteroid that comes as a nebule.
Peak flows don't predict a whole lot for me either, unless I'm so desperately sick that it's not even funny, they don't work very well for me. Of course, it helps to that peak flows tend to add to my bronchoconstriction. Yum!
Intal, 4 puffs in the morning and evening is what your doctor prescribed. Ah. Okay. Nothing wrong with that, I just happen to know that spaced more closely together they tend to work better than high doses spaced far apart. The drugs are great, great ideas, but they don't work as horribly well as one would hope they did. Tilade (kind of like Intal) works a little better but tastes SO NASTY that most people just don't take it. It's not a very popular drug anymore. Nice thing is, you don't have to rinse your mouth if you take it, unlike an inhaled steroid.
Besides, even with an inhaled steroid, I understand that it'd be difficult to do with your work schedule and distance from a place to rinse your mouth -- but hell, if you have to, swig from a water bottle and spit on the ground, or swallow it. It's better than nothing. Or make an effort to eat after you take your inhaled corticosteroid. Whatever keeps the drug from SITTING in your mouth will do the trick.
Pulmicort can also be called "budesonide".
The theophylline thing .. well, they DO call theophylline the 'poison of asthmatics'. It's a derivative of caffeine. I'm sure you know you have to constantly have your levels checked, and I'm willing to bet you've had it explained why. It's because at low levels it doesn't work, and at therapeutic levels it works rather well, and at high levels it causes seizures and heart arrhythmias and death. Be ESPECIALLY cautious if you are put on antibiotics -- the list of drugs that interact with theophylline (to either increase or decrease blood levels) is as long as my arm. And I'm not exaggerating.
The manufacturers ARE covering their behinds with the info they hand out -- do you know what malpractise insurance in the states is like? It's ATROCIOUS. You go into surgery, dr says you're going to have a scar, guy comes out and sues for malpractise cos he has a scar. It's insane. I think the warnings are great to have -- butt-covering is NEVER a bad thing. Doctors aren't omnipresent or omnipotent either -- it's good that you know that -- we DO have to be very aware of what kind of things our medications are doing to us.
Nebs can be used for any drug that's available for nebulizer. That includes everything from Acetylcysteine (which smells like rotten eggs and is used to break up mucus) to racemic epinephrine (which is used to shrink swelling in the throat with things like croup and that) up to and including lidocaine (for things like vocal chord spasm). You could even theoretically take morphine IV solution and nebulize it and give it that way. Lots of things can be delivered via inhalation -- it's just that sometimes the solution has other properties that do things that you don't want happening in your lungs. Like nebulizing alcohol to get real drunk real fast -- it'd work, technically, but it'd also break up your lung's surfactant and make all your little alveoli collapse. Bad thing!
But yes, you've got that right. You can't get Advair for nebulizer, though. You can only get Pulmicort, which like I said, is kind of like Flovent but a little bit different.
Atrovent is not combivent with another name. Atrovent is combivent without the Ventolin in it. Atrovent and Ventolin are two bronchodilators that work two different ways -- Ventolin works by stimulating your sympathetic nervous system (hence why it's called a sympathomimetic bronchodilator) to force the muscles to relax. Atrovent, on the other hand, works by keeping your parasympathetic nervous system from getting stimulated, (hence why it's called a parasympatholytic bronchodilator,) which keeps the muscles from contracting as much in the first place.
The sympathetic and parasympathetic sides of your nervous system are in a constant state of opposition -- so one drug sort of works like taking your foot off the brake of the car and one drug works sort of like putting your foot on the gas. Both will make you go faster, just when you do both at the same time it works REALLY good.
This hormone thing is actually relatively rare (<3% of the population) and so it isn't the first thing that most people think about when it comes to exacerbations of asthma, until the patient actually comes up with something saying 'when I pms then I get all asthma-y'. They know about it -- just within the realm of all the information they have in their head, it isn't the first thing that comes to mind unless you specialize in that sort of thing.
Yes, the brand name for albuterol is Proventil. And Yes, the USA is a tad out of step in many, many ways. Note that we did not adopt the metric system, either.
The hormone thing: bummer. I thought I was on to something, but I did get them refilled successfully--it only took a week. We'll see.
The thing with the medical system here is that it is impacted. I'm lucky and one of the few people I know who have such good medical insurance--probably because my workplace is unionized. Most research used to be done in academia; now it is mostly private. With the move to HMOs, access is more bureaucratic and we have millions of people without any kind of insurance at all, which strains the few free clinics and the ERs. Then we have the state and federal budget crisis, which has caused many facilities to close and access for the lower economic levels is almost nil. We're developing an underclass, much like a third-world country, and an overclass since the corporations have just perpetuated the largest, wholesale highjacking of the middle class in the USA in history. Nary a citizen protested. But I digress.
The pulmonologist's office says do the peak flow. I will do the peak flow; and the hormones; and see if I can get the insurance company to up the amount of Intal I can re-order (with 8 puffs per day, I'm out in 25 days and insurance only permits one every 30 days), to obviate the guaranteed episode on the 27th day or so. I'm existing on low doses of prednisone because I have to work. I'm four years from retirement but am wondering if I can last. I might also bring in a "spitoon" of sorts and take the Intal as you suggested to see if this helps. It would also cut down on the amount of time in the morning it takes to medicate.
Why couldn't you tolerate Flovent?
I will ask about Tilade if I don't get better on the hormones. I don't care what it tastes like. I don't plan on any kissing any time soon.
I also didn't know about the caffeine in theophylline. No wonder my heart is pumping when I'm trying to settle down to sleep. Now that you mention it, I've just had another sort of eureka. I recently switched from espresso to tea, which I bring to work in a thermos. I think I will switch back to coffee and see if that combo with hormones will do the trick. Many thanks for the heads up on the antibiotics.
I'm not saying I mind that you guys have different names for it -- it's actually rather convenient, when someone comes into hospital insisting and insisting that Ventolin doesn't do it for them, when their chart says opposite, and you give them Ventolin anyway, with some Berotec on standby in case they ARE right, and are greeted with cries of "OH WOW this works WONDERS What's it CALLED?"
".... Albuterol."
You were on to something with the hormone thing -- it's real, it happens! Just because it's rare doesn't mean it doesn't happen to anybody.
Yes, the medical system in the states I find incredibly foreign -- I'm used to a healthcare system that's not allowed to turn a profit, and thusly doesn't spend as much money stuffing pockets. Unfortunately, it means we lose a lot of good doctors and other healthcare professionals to the States, meaning we're chronically understaffed. Me, personally, I wouldn't trade working here for working in the US : I'm not a real big fan of getting sued, but that's another story.
Try cutting your intal down to 6 puffs a day, 2 morning, 2 lunch, 2 before bed. See how that puts you through. I have a feeling that by spacing the doses out, and giving the drug a shorter time to get down below its effective dose, your loading dose will not need to be as high. Talk to your doctor about this, however. Even if you have to take a swig of water from a bottle and spit in a toilet, DO IT. The low-doses of prednisone is insane -- then again, I have a bias against the stuff. Are you taking it at 8am every other day? That's the best way to take oral steroids -- mimicks your body's own steroid pattern, and keeps you from getting horribly adrenally suppressed. Again, ask your doctor first.
I couldn't tolerate flovent because for some reason it gave me this incredibly hoarse voice. I think it had to do with the fact that Flovent is absorbed much quicker than Pulmicort is, and if any of it settled on my vocal chords, I didn't have a chance to cough it out or rinse it off before it burrowed its way in there and hypertrophied my favourite muscles. (I sing, so this was more annoying than I thought IMAGINABLE.)
The tilade thing -- hey, whatever works for you. I'm not sure if it actually DOES work better -- just something I've heard mentioned. Worth a try, though, if the Intal's being spaced apart doesn't work better.
There isn't really caffeine 'in' theophylline -- caffeine is a molecule closely related to theophylline -- in fact, back in Tha Day, they used to use caffiene to treat asthma. Since then, they've managed to come up with a few drugs that have varying amounts of real, live theophylline in them. Theo-dur is one of the stronger ones. Aminophylline, if I remember correctly, is not.
