hi,i'm a 31 yr old female that was recently dx hypothyroidism and also graves disease.i was put on tapazole 30mg and had a skin rash and was put down to 15mg.i was feeling fine the gp sent me to a endo who now wants to change my pills to propyl-thyracil 450mg and also start me with apo-hydro a water pill 25mg.i started that only half the dose for the apo hydro but i'm really nervous about switching to the other thyroid med.i'd like to know if anyone has had a reaction with this med?in the next 2 months the endo wants to do rai.i'm not to sure on this either,what's the long term effect?i have alittle high blood pressure,conversyl 4 mg now the endo wants to put it up to 8mg with also useing apo-propanolol 20mg.there's just to many meds and like i said i seem to react to evverything.i do carry a epi-pen in case of a severe reaction but lucky for me never had to use it.i'm just so frustrated and scared of all this new news.any suggestions or comments would greatly be appreciated.

Was the "hypothyroidism" a mistype or a misunderstanding? Graves causes hyperthyroidism.

I was switched in the opposite direction from ptu to tapazole cause of a skin rash. I didn't react to the tapazole after the switch. I have multiple med allergies and also have access to an epi pen that I've never had to use. I was also warned that if I ever use it to head straight to the hospital cause hyper and epi don't mix real well.

I'm a little curious as to why your doc is using an ace inhibitor in combination with a diuretic/beta blocker combo. Seems to me that the hypertension may be secondary to the hyperthyroidism and a beta blocker alone might do the trick. A combination of ptu and a propranolol or one of the other betas alone is often enough to control a hypers bp and heart rate. He may have his reasons though. Have you any other medical conditions?

I'm not a big fan of rai especially if medications can control the condition. As I look at it, if a patient feels good, leave it alone and see what happens.

There's nothing to be really scared about. You're allowed to be frustrated, annoyed and maybe a little angry. It's a terribly annoying disease this hyperthyroidism is but I'm into my 49th year of it and still hanging in strong. Just hang in there and hang around here. You'll find a lot of support and answers to your questions. You'll never be alone with this.

Take care,
Helen

Did they test you for Hashimoto's as well? Or are they running under the archaic assumption that you can only have Graves or hashimoto's. It is possible to have both Graves and Hashimoto's. My mom and one of her four sisters did. I do.. but my Endo dismissed my low positive for Graves in favor of my very positive Hashimoto's.

What are your TSH, Ft3, Ft4 levels and ranges? Have they tested your carnitine levels? If these are off they can cause the nasty rashes with Graves. My Aunt N has just Graves and she takes daily L-carnitine supplements OTC and they keep the nastier side effects in check. Do not just start taking it with out getting your MDs approval.

As to graves and hypoT.. well it is very commone that undertreated or untreated Graves can run your thyroid to death literally. It is very common in Graves patients to end up as Hashimoto's patients. I still wonder if this is the bodies way of regulating too much thyroid hormone. No confirming data on it though. My Aunt is on Tapazole and uses a beta-blocker as well. Her rashes and issues were due to the tendancy for carnitine depletion and supplementation fixed her issues. Maybe something similar is occuring for you. I know rashes was her main complaint

MG

Mg
How long has your aunt been on Tapazole and how old is she? Do they test her liver enzymes? What dose is she on? Curious about how other docs handle this disease besides pushing the RAI?