that would depend on a few things. how old is she? how bad is it? how much does it bother her? my daughter suffered from age 12 with bad acne. we tried everything and the only thing that has worked consistently is yasmin and spironolactone. before that we went through a list as long as your arm. some stuff helped temporarily (such as antibiotics). sometimes over the counter stuff helps if it is very mild. sometimes, you need more.