With my reflux, I tried all the PPIs. ALL OF THEM, and they all gave me bad lower abdominal cramping and stomch pains etc. Finally my doc put me on ranitidine (zantac) at a dosage of 300mg 3 to 4 times daily... It worked for a good long time, but I had a nissan 3 weeks ago and dont take anything now. The nice thing about the zantac is that it is pretty benign, so I dont think I had any noticable side effects.