I have had the exact same thing happen over the course of the past 3 years. The allergy shots (mold, trees, grass and weeds) don't help me much (if any), but still get a bad reaction to them (haven't reached maintenance). Anyway, I have a deviated septum, no question about that. But the three CT Scans indicate that there are still openings for mucus to flow. I've seen three ENTs. Only one recommends surgery, the other two say it will not help. I'm therefore avoiding surgery for now.

I also take Flonase (recently have been putting Pulmicort in a lavage bottle instead), which helps slightly. I recently took prednisone for the first time and found that it worked wonders... I did that in conjunction with antibiotics and have felt better. Probably just a matter of time before I get all inflammed again though.

I'm going to explore fungal sinusitis as a possible contributor. I don't have any immune system deficiency, but based on what I've read, you don't necessarily need to have a deficiency to have fungus cause chronic problems. See [url]http://www.webmd.com/content/article/84/98134.htm[/url].
I suspect that since I'm very allergic to mold, it is likely contributing to my problems. I posed this question to others earlier, but didn't receive any insight in to the use of prescription anti-fungals. It may be something you want to look into as well.