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   How safe is Promethazine (Pregnancy board)

25th October 2004
I have been pretty sick with m/s and I spoke with the dr. He put me on Promethazine. I am trying to figure out what class it is in and can find nothing online and I am not too sure where to look. I just want to know how safe it is. I have Chorns and am on a restricted diet of no wheat, no dairy, etc. So those things most people use to fight m/s like saltines and stuff I can not have. Since there was nothing I could do to fight the m/s he put me on this. Not to mention I was sick with m/s all day and all night. I have been taking it and it has helped but I am more tired then normal from it. Due to it making me so tired I am worried it will have a negative effect on the baby.
27th October 2004
there is a medicine that is safe to take and it is called Zofran...it is very expensive so insurance would probably be the only way to get it (it is around 700 dollars for 30 days!) but your insurance should cover it...talk to your dr. about it before you take the promethazine....zofran is sooooo much safer for the baby.
2nd November 2004
did anyone in here mention that promethazine is the generic for phenergan? but i looked on a website and this is what it said about the drug and babies, just for a little 411...Phenergan is in the FDA pregnancy category C. This means that it is not known whether Phenergan will harm an unborn baby. Do not take Phenergan without first talking to your doctor if you are pregnant or if you are planning a pregnancy (promethazine is the generic for phenergan)
9th November 2004
Actually, phenogren, or promthazine, is safe in pregnancy, it is classified as a C because of the class of drug it is associated with, and becasue not enough research has been done on the medicine. The thorazines i think it is. My husband and MIL are nurses, and give promthazine to pregnant women all the time, i also see a dr who specializes in maternal fetal medicines and she said it was fine also. But it is very easy to build up a tolerance to promethazine and it won't work anymore. Last year i was very sick and taking 150mg of it a day and it wasnt' helping, normal does is about 10-25mg. But anyway zofran is a better drug it does work better. But zofran contains phenylalanine which in people who have certain diseases it doesn't get processed correctly and can back up in your system and cause serious problems, but you would probably have to be takign ALOT of zofran to have that happen. Becoming serioulsy dehydrated during pregnancy, or malnutrioned, is a very serious problem. And most likely poses more of a problem than takign phenogren would cause.
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