I Have Talked To A Few People In Here, And I Have Another Question, I Have Cronic Back Pain For 3 Years Now, Had Back Surgery In 2002 On L4-l5-s1, And I Tryed Methadone For The Last 6 Months, It Worked For Pain, But Way To Many Side Affects, So Now I'm Back On Oxycontin, But What Should My Family Doctor Have Started Me Out At... Because What He Gave Me Is Not Enough,and For The Last 5 Days I've Been Really Sick And In A Lot Of Pain, And They Said It Will Take 2 Weeks Before Methadone Is Out Of My System, And I'm Going Threw Hell,
2 Question, --- Is There A Difference Between Real Oxycontin Like The 10-20-40-and 80's And Compounded Oxycontin, I'm Getting The Compounded Stuff, And They Can Make Any Dose, They Tryed To Tell Me It Would Last For 12 Hours, And Thats A Lie, When I Took It Before I Only Got 4 To 5 Hours Of Relief, With The Real Oxycontin I Get At Least 10 Hours, So Can Some One Answer These To Questions,

hello bucky. what dose of methadone were you on before switching back to oxycontin? and how does the pharmacy say that the compounded oxy works? does it have a time release like oxycontin? I guess if it is compounded it is in capsule form which makes me wonder if it truly is long acting. if the pharmacy puts oxycodone in a capsule plus the fillers than how could it be long acting?? i would think that it would release just like an immediate release drug like percocet, unless it has some sort of special capsule but that to me does not make sense either but i am no doc, pharmacist or even scientist for that matter. but this would explain why you are only getting 4-6 hours of relief. the real oxycontin states that it should last for 12 hours and you all know that your lucky to get 8 hours of pain relief with it so most docs will prescribe it 3 times daily. so something that is compounded like that in my mind could only be short acting. is it prescribed every 8 hours? I am not sure if you mantioned that but i hope your doc ups your dose so you can get proper relief.

I looked back on previous posts of yours and it looks like you were on 45mg every 12 hours of meth. So what dose has your doc put you on in order to start off with your transition from meth. to oxycontin?

does anybody out there know what a good conversion would be when converting from 45mg of methadone twice daily to oxycontin?

thanks for the replys, everyone in here is a lot of help, i'm am still sick after a week now and my doc is slowly rasing my dose of oxycontin, had to go to the er 3 times, they gave me a shot of delodid , helped a little but not much,and about the compounded, the pharmacy said their is filler in it and it is 8 hours relief, they have different capsels for how quick they disolve, and i'm up to 30 mg now and dont have much effect yet, when i had this compounded oxycontin before it only last up to 4 to 6 hours, compared to the real oxy i got 10 to 12 hours relief, and they put stuff in this so it cant be abused, that is a good thing, so no body will steal it, the phar said, i told the pharasist that if some one stole my meds they still could get high, they could just take a hole bunch, bla,bla,bla, anyway, does any know where i can find information on compounded oxy to the real stuff, the phar is making lots of money off this, he is charging the same price. thanks for the replys, and i hope i feel better soon, i went and got a referrel to another sergeon, to see if he can do something for me, i'm only 30, bye for now

I too have a really hard time understanding just how any pharm can actually compound its own oxycontin,really.The dellivery systems are very different than those founf in other meds.I think you are actually getting only some sort of compounded version of oxycodone delievered as oxycodone,you know what I mean?as far as I know,any sort of time release meds that are in a capsule form still have,inside the cap,tiny "beads" that do the time release part of the process.Look at your capsules and see if there are tiny bead looking things or if it is actual powder.or ask the pharmacist directly,just what exactly IS in there.eveything and anything.you DO have the right to know just what they are putting inside these caps.and since it is not listed in a PDR you cannot actually look up this info on your own.I would be willing to bet that you are not getting the actual effects of a true oxycontin type of time release med.It just does not sound possible as far as I know.SHORE??i could be totally wrong here(it has happened in the past,lol) but really i just don't know about this.

you can also go to a different pharm or ask your doc to give you an rx for real oxycontin.just tell himthat whatever it is this pharm is giving you just is not working up to par.this whole thing just doesn't 'sound' right to me,really.you DO have a right to know just what is in there and to ask the pharm just what in the heck actually MAKES the time release delivery actually happen.I am really really curious about just what all this pharm is actually placing into the caps that you are taking.You should be too.you DO have the right to know this just incase he tells you you do not.if you have any problems in obtaining this info,just contact the local chapter of the board of pharmacy for your state.Please let me know just what you find out,K?I hope something starts working here for you soon.Marcia

Hey Bucky, Aside from whatever the conversion, although meth binds to just about all the receptors tha oxy does, so a switc n that directionis easy compared to the opposite. Methis unique in the receptor activity is creates. Mainlyit blocks the NMDA recepotor which controls tolerqane to pain and tolernce to opiates. It's why Ketamine is used n compounding and other crouties, but it had side effects too.

Meth also has more DElta receptor activity than oxy, delta activity doesn't have the eurporic effects like tehe MU reeptor, btut both drugs also ahave MY activity whewre oxy has little Delta receptor activity. These small variations and some other unique qualties of eth make what your experiencing called transitional withdrawal. Even if there was a magic number that gaurenteed euqual relief you would lkely still feel cruddy, so unless you way under dosed on oxy you likely going to feel wrotten any way. 2 weeks sounds about right but you will probably start feelin better around day 10 and by 14 with the right dose of oxy you should be fine.

Compounding LA Oxy can't be that much cheaper. Oxyis expensive but so is compounding. MOst likely they are using Dextromathorphan as an agent to prolong the effectiveness and increase pain tolerance because DXMis also a NMDA receptror blocker. OxyContin which is pure oxycodone has a rease desinged by to release at certain points. The drug they are using to extend the coumpounded Oxy I'm guessing is DXM because i have seen it used to create a LA version of hydrocodone. It was need 3-4 times a day, butthat's better then the lucky to get 4 hour meds. Even the name brand OxyC needs to be dosed every 8 hours but Purdue's clam to fame is their 12 hour duration.

Why still compound the meds. Is it a way to fly under the radar as far as prescribing OxyContin or maybe he's done you a favor by adding the DXM to give it some of meths properties so the transition isn't as bad.

As far as convrsion, I haven't seen to many charts that acuretly predict methadone's strength. Most are only god for single dose cmparision beause they don't acount for the 5 days of build up before you steady out. I've swithed meth to morine back t meth and back to morphine and it also ended up at %:1. 120mgs of meth was equal to 600 mgs of mrphine. Oxy is stronger so 3:1 or 4:1 is probably more realistic but docs tend to start on the low side, often the very low side. RAther than self medicate, if you just can't take it, let the doc make the call. I stuck it out knowing there is light at the end of the tunnel if you have confidece your doc will titrate the oxy dose to a level that works. Whether it 3:1 or 5:1 or & 7:1 what works for you is more important.
Good luck, Dave

Yes, I have been reading this post PURELY out of interest (and IT IS INTERESTING, ISN'T IT??!!). What is the need for the compounding?

Shoreline, I must admit that you truly have it over me in your understanding of compounding!! After I read your explanations, I need some BT meds to help me!! Please know I'm kidding you. You have such tremendous knowledge about these sorts of things that I'm sure we all possess the appropriate respect for you!

Nonetheless, what is the need for such specifically-dosed compounding of the long-acting (LA) medication in this case?? Whatever the case...we are greatful for those that offer the services of performing such tasks!!

I'm sure we would all like to know WHY the OxyContin (whether it be Brand or generic) needs to be compounded in such an exacting manner IN THIS PARTICULAR CASE. Please let us know how this saga plays out. Honestly, this is running like a Pharmacy School Soap Opera!

Sincerely,
Jon (Conductor)

P.S. I often jest with many of you, but I do take our problems seriously and wholeheartedly maintain the interest of us all!! Thanks, everyone, for your anecdotal (yet utterly vital) information.

I think one of the reasons he does not get the generic oxycontin is because he is in Canada. Here in Canada there is not a generic version of oxycontin yet. I am on oxycontin brand name and have been for a few years, it is dosed 3 times daily for me which works alot better than the 12 hour dosing that I started out on. At one point my doc decided to try me on the compounded oxycontin. There is a pharmacy in my area that specializes in all sorts of compounding and specialty items. It was when we came to an agreement that I needed an increase in my dose, he thought that it would be a good idea to try the compounded oxy because we could put the dose up by whatever we needed unlike the brand and generic. I am not 100% sure of what exactly was in it. Clear small capsule, oxycodone, ginger, and I believe dextromethmorphan was also an ingrediant. They also do another oxy that has the same ingrediants but instead of ginger, cayenne pepper is used I would think that is to try and prevent snorting. As far as the ginger one of the pharmacists said it was to prevent and help stomach soreness which is sometimes a side effect of opoids. Anyway they are prescribed as an 8 hour med, but I found that 5-6 hours would be the max that I would get for relief which made me wonder how the compounding oxy could be long acting?? I was on the compounded oxy for less than a month because I was not getting the relief that I was before on the brand, they worked great for 5-6 hours but that was it. so they did work just not long enough. I made an app. half way through the month brought the remaining meds and my doc wrote another script for my regular oxy. Oh yeah I also had a hard time trying to get my drug company to cover the compounded which I won't get into right now. I have really good coverage now my plan covers 80% which leaves me to pay only 20%, and my girlfriend has 75% coverage leaving her to pay 25%. So my plan covers 80% and her plan which I am a secondary on covers the remaining 20% so I now get 100% coverage for all my meds which is sooo awesome because the oxycontin is so expensive: for (90) 40mg tablets $245 and for (90) 10mg tablets $100, thats some pretty big savings.