I went insane on lo ovarl generic, my moods were out of control. I was angry all the time, i was restless, i have gained weight. I hope that now i have switched to yaz since its a different combinations of stuff it will do better for me. I was on lo ovral for like 4.5 years and i just started to really notice the side effects or how my mood was getting way out of wack. hope that helps. if you research the certain kind of medicines in birth control you can see which work and dont i mean you cant keep taking the same kind if it isnt working for your body. :)