i agree its possible anxiety, i went to my urologist 2 weeks ago for bladder pain, he prescribed macrobid and sent me on my way.after a week of taking them,i was still in pain but much more so i went to the er. they did x-rays,bw,and urine cultures and every thing was fine??im a guy and worried it was prostatis again but my prostate was fine. the gave me pirodiux ,forgive my spelling, well it helped and turned my pee red!!!i took 2 ov the 6 pills they gave me and have not had anymore pain,knock on wood.i was very tense and stressed during the bladder pain episodes.