Not so sure you can blame this on niacin... after all, Advicor is an extended-release niacin / lovastatin combination and likely has it's own unique side effects unlike any other medication.

I've been taking 3000 mg of Niaspan each day for the last 20 months without any dry-mouth... so maybe it's from the statins or a combination of the two medications.

Come to think of it... I don't even remember getting dry mouth from any of the statins during the 6 years I took statins... and that includes Pravachol, Baychol, and Lipitor.

Sounds like this is just unique to Advicor.