I took daily doses of psyllium for many years prior to taking BP meds but stopped about 1 month after I went on the meds because of concern about the "absorption" of the medications. Since taking the daily 10/40 Lotrel dose, I've noticed an increased tendency to constipation, but not particularly so since stopping the psyllium.

I'd be interested on opinions about a good time to ingest psyllium relative to the time meds are taken and also, if magnesium supplements offer much benefit in this regards.