I took Lo-Ovral over a year ago and I hated it... I gained weight and got really moody... so I switched to Yasmin and I stayed on Yasmin for over a year... I lost all the weight gain from the Lo-Ovral and didn't have any problems, except for cramps... I had lots of cramps... Nothing I couldn't deal w/, tho. Then, recently, I had to switch to Desogen b/c Yasmin was too expensive... So, now I'm taking Desogen and I HATE it. I have gained 7 pounds... I can't seem to get rid of the weight.. I am more moody than usual.. and I feel like I have a decreased sex drive.. Ugh. I am switching soon...!!!!!