Thanks so much for the info! Ive heard so many reviews about Ortho being amazing, and others had a horrible experience on it. I broke out really bad from Levora and its localized to my chin. Its so aggrivating..So I hope Estrostep might regulate my hormones and help level things out. I guess its trial and error... Im starting to realize that no matter what anyone tells you..you have to just try them for yourself.