I tried red yeast rice and it did nothing for me. Tried 10 mg Lipitor and all of my muscles painfullly locked up. Took a year to recover. After four years, tried again, and Im on 80 mg Lescol XL which reduced my LDL from 308 to 103. I tried 500 mg no flush time release niacin from Wallys mart twice a day. It lowered my LDL another 10 points to 93, raised my HDL only from 39 to 40. This greatly improved my ratio though. So I dont know if the RYR is helping you, but the niacin only helped my LDL.. so Im going to stay on it.