My body had locked up on 10 mg Lipitor after 9 months as though rigormortis had set in. I stayed away for 5 years. My current doc convinced me to try a different type of statin. There are natural, and synthetics. They are processed in different parts of the liver. I tried Lescol, it is weaker, and it took the 80 mg Lescol XL dose to get my LDL down to 99. So far no problems whatsoever but I am taking CoQ10 for the heck - and rumor - of it.