A year and a half ago, my total cholesterol was 255 and my CRP level was a whopping 5.4! The doctor was really upset about the CRP. He put me on Lescol XL and told me to lose 30 to 40 pounds. He also said to cut out foods that promote inflammation and cause higher CRP, such as red meat, anything made with white flour or trans fats (hydrogenated fats), and peanuts. I was so scared that I did pretty much eliminate the foods he said I shouldn't eat. Six months later and 30 pounds lighter, my total cholesterol was 169 (subtests and liver enzymes all fine) and my CRP level was down to 2.1, which the lab sheet said was average. Another test six months later showed that while my cholesterol had crept up to 190, my CRP remained low at 2.0. I want to get off the Lescol or at least reduce the dose, but my doctor says that would be a mistake, since my total cholesterol is high normal now. The stories I hear about statins worry me. I do take 100 MG of CoQ10 each day, since I'm concerned about muscle damage. (And after all, the heart is a muscle.) I will keep on avoiding the red meat, etc., since I noticed such a big drop in CRP level, but I'd really like to cut the Lescol dose. Wonder whether the CRP and cholesterol would go up again if I dropped the Lescol, despite the weight loss. Wish we knew more about all this stuff.