I tried Kariva as well when Ortho Tri Cyclen (Tri Sprintec) gave me horrible mood swings. I was on Kariva for maybe about 2 weeks when I noticed my appetite was completely gone and I lost about 10% of my total body weight, and I'm very small to begin with. Also, I experienced terrible depression and mood swings. I was taking a vitamin B complex throughout my entire time of trying out different BCPs and it never seemed to work. I eventually went off BC completely.