My sister age 45 was diagnosed in January with Stage IV - it has spread to her brain, heart and ovaries - she is done with radiation and is taking Iressa they have only given her 6 months to live and were almost at 2 already. She is very energetic and in good physical shape so she has that going for her but she has a lot of headaches. She is trying to enjoy what time she has left but I worry about what will happen when she gets bad because right now she is doing so good. Hope your friend is doing OK keep me updated if you don't mind.