I didn't take Actonel but Fosamax gave me a fit with my GERD. After a month I couldn't take it anymore and my rheumatologist switched me to Didronel cycles for my osteo. It sounds like your doc needs to switch your osteo drug or you need something stronger for your GERD other than Pepcid. If you still have the problems after medicine changes then further evaluation needs to occur.

Shandi