You should call the endo. I had the same problem and I had to lower the florinef. Now I am off the florinef and my legs and ankles do not swell nor get hard.
You need to have some blood work done.

Betsy

Talk to me about going off of Florinef. I just left the hospital from having a cat scan on my kidneys. They noticed how swollen I was in the legs all the way up and the ankles. My Endo was contacted, and now I have to go off the florinef gradually. I feel great other than the kidney stones dizzy wise, so I am scared.
I have to taper to one every other day for two weeks and then go one day on one day off for another two days. then quit.
What did you do?:confused: