If you think your acne is hormonal, Ortho Tri-cyclen and Desogen both have anti-androgenic (testosterone-binding) properties, which can help a lot. I've tried OTC and it didn't work at all for me (maybe it made it worse) but I'm on Desogen now and I love it. My skin looks a lot better and my periods are SOOO light. Yasmin is also good - it has a light dose of spironolactone, which effects potassium levels and stuff. I've never tried it but apparently it's been really good for other people. Hope this helps :) Good luck :)