I have been on Ortho Tri-Cyclen for appproximately one month. I think I have been experiencing side effects such as depression, migraine headaches and nausea. I know there is an adjustment period. However, I noticed that when I am taking the placebo pills, I feel like my old self (no depression). Anyone else experience this?

I talked to my OB/Gyn and discussed with her the possibility of taking Desogen to help with my acne. Anybody take this pill and did it help with acne? Also, did anybody take both pills and which, in your opinion, worked the best at controlling their acne? Thanks a lot for your replies in advance. Catch you on the flip side. :)

I've taken OTC lo (1 1/2 months), Yasmin (3 1/2 months), and Desogen (4 months). Desogen has cleared my skin just as much if not more than Yasmin, without the initial breakout, the nausea, and the breakthrough bleeding. So I'm very happy on it. You do have to consider the slightly higher risk of blood clots and whether it is worth it to you though.