Well I'm a bit different than the others :) I'll take any drug that will clear my skin :) Spironolactone is great! And my endocrinologist says it is one of the safest drugs in existence if you are in good health. No risk to the liver or kidneys.
My dermatologist doesn't prescribe the pill but I've heard of ones who do. They usually require that you get a gyn exam anyways. I had a gyn prescribe Yasmin for my acne. Luckily it doesn't have as high a risk of serious side effects as Diane. I did have some nausea, so I've switched to Desogen and it is also very good.

Wow, ok, thanks you guys, but now I'm confused..............

Spironolactone-- is it good or bad to take long term? Will the effects of it wear off?

Whatever is in Diane 35, WORKS for me, (therefore, Ortho Tricyclin does not work at ALL) I heard that's what is in Yasmin... So why is Yasmin better for you than Diane? Do you think my body would be less out of wack on Yasmin?


So I guess this is what I need your help on, comparing what's in Spiro, Yasmin, and Desogen in comparison to Diane 35.

Quote from stardusted1:

Wow, ok, thanks you guys, but now I'm confused..............

Spironolactone-- is it good or bad to take long term? Will the effects of it wear off?

Whatever is in Diane 35, WORKS for me, (therefore, Ortho Tricyclin does not work at ALL) I heard that's what is in Yasmin... So why is Yasmin better for you than Diane? Do you think my body would be less out of wack on Yasmin?


So I guess this is what I need your help on, comparing what's in Spiro, Yasmin, and Desogen in comparison to Diane 35.

I was on spiro for a a year and 1/2 or so and, even thought it stopped working, I can't say that it had any bad effects at all (just that it was a diuretic and I had to pee all the time! :)) I think it's fine to take long term, but everyone's different. Ask your doc.

Spironolactone is an anti-androgen. The progestin in Yasmin is derived from it and is also anti-androgenic. Its a different anti-androgen than what is in Diane and doesn't seem to have the high risk of blood clots. Ortho has a different progestin which is not anti-androgenic. The progestin in Desogen is also not anti-androgenic, but for whatever reason it seems to be one of the safer ones for acne prone skin.