I had been on OTC for about 9 months, and it definitely didn't clear anything, and my acne actually got worse too (but that may have been because of stress). I'm on desogen now, which is supposed to be good too, and my face has actually been clearing. I can't tell if it's because of the new pill, or the new cleansing routine I've been using, or both. Anyway, OTC didn't help me at all, but everyone's different. Hope it works for you :)

bbsq... I'm on Desogen with no problems. I haven't had any zits and my skin is clearing up more, but I'm not sure if my new rosacea med is helping too? At any rate, my doctor felt like it was the second best pill for acne (behind Yasmin).

Most progestins are derived from testosterone. They have slightly different chemical structures, so some act more like testosterone than others. (They still can decrease testosterone though by shutting down the ovaries).
Ortho Cyclen has norgestimate which isn't very androgenic. The two progestins that are *theoretically* safer for people with acne to try are desogestrel and drospirenone (which is the theoretical best because it is the only progestin available in the US which isn't derived from testosterone; it is derived from spironolactone so that it not only shuts down the ovaries, it binds to testosterone coming from the adrenal glands to lower it even more). Pills with desogestrel are Desogen, Cyclessa, and Mircette. Yasmin is the only pill with drospirenone.
You also have to look at the estrogen dosage. It can help counteract the testosterone effects of the progestin.
And keep in mind this is all theoretical. How you react to a given pill might be different than how most people react.