Oh I can't even remember all the meds my son was on.. I know Adderal was one of them and there was a weight concern as well as the fact that he still wasn't getting it. There was Clonidine too for a while which I was leary about at first considering it's a med to control high blood pressure in adults. I guess if you like the doctor and trust him then you can decide. My son had a good doctor who would say..."hey, if there's a problem call. If you don't think it's working you can add X amount and try that. If it still doesn't work call me".