I only used it for a week, but it dried out my skin like nothing I've ever used before (and I've used Cleocin, 10% Benzoyl Peroxide, and either Retin-A or Differin all at the same time and didn't have problems). I used the one with 3% clindamyacin, which has to be kept refrigerated (another pain). Maybe the 1% one wouldn't be so bad.