Well everyone......I have been using Differin and Cleocin T regularly since Oct 29th of this year. I can't believe the difference it has made! I am so happy about this. When I started on the stuff the initial breakout was so horrible for me. I got acne where I have never had it before on my face. I still have 2 spots that are clearing slowly. I read somewhere that Cleocin T should be applied 2 times daily so I started that too. I also quit using the Cetaphil cleansing cream. I went back to using my normal Caress Body Wash on my face. As soon as I did this my face is like awesome now! Differin has made such a difference with me. I use Cleocin T in the am and Differin on top of it and just Cleocin in the pm before bed. It has taken a while for it to take full effect but wow is it working now. I had little drying and redness. Barely noticeable. I think what made the difference with the Differin not drying my skin out is that I started to use the Cleocin under it. I don't use any lotion at all on my face. It's like my skin has evened out now. I use to use it regularly. I read that Differin is the topical equivalent to Accutane. Not sure if it really is but it has done wonders for my case!!!!!