My biggest issue with dexadrine or dexstrostat is that -first of all when I began it, it knocked me out cold- had to take it at bedtime for a couple of months- an unusual response I am told- -also benadryl doesnt make me groggy-I switched to ritilin sl because I crashed everyday when dexadrine wore of- usually as I was coming home to manage the homework scene with my autisitic son and fix dinner. other than the crashes every four hours I loved it- well ok now I am remember one other side effect- we live in upstate timbuck two- and for what ever reason pharmacies sometimes have difficulty getting and stocking these drugs - can take 2-5 days- and you cant just take a break from dexstrostat- your head swells up like the worst college hang over you could ever remember- I have high blood pressure as well and if I missed a dose my blood pressure shot up through the roof- also unusual I think. If its a weekend and I only 8 hours of medication instead of 12 it is easy to do and if I cant get my ritilin I can function manageably on lots of caffine - no head aches! -meme