I have used Advair for about 2 years..(or 3?). In my opinion, Advair is a wonder drug. I had no problems or complications other than my appetite increased. Advair is so expensive, however. So this week I began using Azmacort, instead of the Advair, to save money. I have had several side effects which include; restlessness, insomnia, exhaustion, and an itchy-watery eye...plus, I do not feel like I can breathe deeply using this drug. I will switch back to Advair.