Hi Tigger. Its not common to have RLS with MS, however it is INCREDIBLY common to have muscle spasms with MS....muscle spasms, especially at night a a refrequent complaint......did you dx yourself with RLS or did a doctor?

If you have an MS dx, most doctors will prescribe you a muscle relaxant or something similar to take at night, to help you control this; however it also depends on what MS meds you are already taking...if you take an interferon, REbif, Avonex, or Betaseron, you can take muscle relaxants- but you cant take some of the RLS meds (requip, etc) they raise the liver functions too much.....so, please, first make absoutely sure its RLS and NOT Muscle spasms, which can feel very much the same- and second, make sure your doctor knows what you are taking overall....most neuros dont treat RLS, so if you are seeing a GP for that, be sure he is aware of what the other doc is prescribing.