To zuzu-Thanks for your response. I am currently on Avapro, and my blood pressure reading is 150/90. When I went to the emergency rooms in the past my blood pressures fluctuated around 210/102--while on hydrochlorothiazide. The blood pressure is just impossible to get good control over with the hyperparathyroidism. I am anxiously looking forward to having surgery in hopes that my quality of life is better. I keep wondering if taking the hydrochlorothiazide triggered my hyperparathyriodism or if it just increased an existing but minor imbalance problem?