21st May 2004
Clark and Poakfish,
You both are doing really good things. I don't know how long you've been on those regimens but it does take 3 - 6 months to see results. You both are attacking DHT in several different ways. Depending on one's sensitivity level that's exactly what more of us may have to do.
So the BEST of the best ways to deal with DHT is:
1. Anti-androgens
a) Reduce overall steriod hormone synthesis -
1. Insulin Balancers - Diet, Prescriptions (Avandia), Supplements (ALA, Chromium Poly.), Fiber (Glucomannon)
2. Fat Metabolizers - B5 Therapy, Guggulipid, NAC-Vit. C
b) Bind Free-Testosterone - Estrogen (SHBG)
c) Increase Aromatase - increases testosterone conversion into estrogen, which means less that will convert to DHT! How?
2. DHT Inhibitors
a) Inhibit DHT enzymes - [Accutane - temp. effects], Flutamide, Spironolactone, Propecia, Avodart, Saw Palmetto, Stinging Nettle*, & Zinc-B6 (this may or may not contribute to increased or decreased sensitivity overtime).
b) DHT analogues - GLA (Evening primrose, Pumpkin Seed, Flax seed oils), Saw Palmetto (sterols), Beta Sitosterol, Soy isoflavones (Eqoul-Diadzein & Genistein), Green Tea, Pygeum, Stinging Nettle*. These look like DHT structurally, but aren't. They bind to the Androgen Receptors to block DHT from binding, thus it can't interact with those receptors. (this may or may not contribute to increased or decreased sensitivity overtime)
c) DHT binders - something enzyme or hormone that specifically binds to DHT to deactivate it. Does it exist?
3. Breakdown DHT - Estrogen is rumored to catabolize this and is also rumored to inhibit it's break down. I haven't found anything to support this either way. An Enzyme created this so an enzyme should destroy this, but how? By blocking the Androgen Receptor sites, DHT is supposed to be broken down and excreted. However, at this point, it seems that science doesn't know how increase that effect (safely).
So as you can see, there's hope, but there's so many questions when it comes to DHT and unfortunately there's still not enough answers. Any of you that want to be scientists please do so. There's plenty of mysteries that have yet to be solved. ;-)
HTH
P.S. *Something fascinating for you males (unsure for us females), is that Stinging nettle binds to both the Androgen Receptors to Block DHT , and also SHBG to block Free Testosterone. Now usually you would want Free Testosterone bound to SHBG so that it won't aromatize, but since you are blocking DHT, by leaving Free Testosterone free, you are able to maintain your libido....
You both are doing really good things. I don't know how long you've been on those regimens but it does take 3 - 6 months to see results. You both are attacking DHT in several different ways. Depending on one's sensitivity level that's exactly what more of us may have to do.
So the BEST of the best ways to deal with DHT is:
1. Anti-androgens
a) Reduce overall steriod hormone synthesis -
1. Insulin Balancers - Diet, Prescriptions (Avandia), Supplements (ALA, Chromium Poly.), Fiber (Glucomannon)
2. Fat Metabolizers - B5 Therapy, Guggulipid, NAC-Vit. C
b) Bind Free-Testosterone - Estrogen (SHBG)
c) Increase Aromatase - increases testosterone conversion into estrogen, which means less that will convert to DHT! How?
2. DHT Inhibitors
a) Inhibit DHT enzymes - [Accutane - temp. effects], Flutamide, Spironolactone, Propecia, Avodart, Saw Palmetto, Stinging Nettle*, & Zinc-B6 (this may or may not contribute to increased or decreased sensitivity overtime).
b) DHT analogues - GLA (Evening primrose, Pumpkin Seed, Flax seed oils), Saw Palmetto (sterols), Beta Sitosterol, Soy isoflavones (Eqoul-Diadzein & Genistein), Green Tea, Pygeum, Stinging Nettle*. These look like DHT structurally, but aren't. They bind to the Androgen Receptors to block DHT from binding, thus it can't interact with those receptors. (this may or may not contribute to increased or decreased sensitivity overtime)
c) DHT binders - something enzyme or hormone that specifically binds to DHT to deactivate it. Does it exist?
3. Breakdown DHT - Estrogen is rumored to catabolize this and is also rumored to inhibit it's break down. I haven't found anything to support this either way. An Enzyme created this so an enzyme should destroy this, but how? By blocking the Androgen Receptor sites, DHT is supposed to be broken down and excreted. However, at this point, it seems that science doesn't know how increase that effect (safely).
So as you can see, there's hope, but there's so many questions when it comes to DHT and unfortunately there's still not enough answers. Any of you that want to be scientists please do so. There's plenty of mysteries that have yet to be solved. ;-)
HTH
P.S. *Something fascinating for you males (unsure for us females), is that Stinging nettle binds to both the Androgen Receptors to Block DHT , and also SHBG to block Free Testosterone. Now usually you would want Free Testosterone bound to SHBG so that it won't aromatize, but since you are blocking DHT, by leaving Free Testosterone free, you are able to maintain your libido....