I took 40mg of nexium and protonix for 3 months without any improvement of my sore throat. I then doubled my dosage and my symptoms have gotten a lot better. So it's possible you do have LPR and still not respond to ppis if the dosage is too low. Unfortunately I've traded in the sore throat for daily sore chest. I don't know if it's a reaction to the protonix, heartburn or esophageal spasms. My chest pains usually peak after I eat, then tamper down, only to rise up again after I eat and since I eat every 2-3 hours, it's a real hassle.

My acid reflux problems only became very apparent after 3 weeks of augmentin. Prior to the antibiotics the doctors were treating my symptoms as a respiratory/sinus problem. ENT said I had 'silent' reflux. It's not silent anymore.