Medications that can lower the levels of Coq10 in the body include statins for cholesterol (atorvastatin, cerivastatin, lovastatin, pravastatin, simvastatin), fibric acid derivatives for cholesterol (specifically, genfibrozil), beta blockers for high blood pressure (such as atenolol, labetolol, meoprolol, and propranolol, coreg) and tricyclic antidepressants medications (including amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine), and some anti-diuretics including HCTZ.... I have another more complete list from the NIH (national institute of Health) but have to look for it.... The cerebellum (part of the brain) is very sensitive to a number of drugs, and is especially sensitive to the lowering of Coq10.