1st August 2004
Good morning Rahod,
I demand 20 points in the game of life for having finished the 37 page .pdf.
My only quibble was the emphasis put on CRESTOR'S differential effect on HDL-C (as opposed to Lipitor.)
AZ report dismal +2% to 6% HDL-C with atorvastatin and I KNOW I got a 25% increase in 30 days with 20 mg. Lipitor.
Other than that a good read.
Hey guy, you're a good researcher. Can you see what you can dig up as to the link between statins and myalgia. Not the incidence, but rather the CAUSATIVE rationale. I think it's real and simply cannot find what it is about the reduction of cholesterol (or the mevalonate precurser) that HURTS. Can it have to do with alternate chemicals that are produced INSTEAD of the normal pathways. Or does the statin inhibit OTHER enzymes than just the Hmg_CoA. Enzymes perhaps that the muscles need for proper functioning?
Perhaps, I'll never know?
(Proximate reason for this is reawakened concern is that my one weeek without Lipitor trial has decreased the pain in my shoulder- I THINK!:D:D...and I haven't taken a SINGLE placebo:D:D)
More on that later.
I demand 20 points in the game of life for having finished the 37 page .pdf.
My only quibble was the emphasis put on CRESTOR'S differential effect on HDL-C (as opposed to Lipitor.)
AZ report dismal +2% to 6% HDL-C with atorvastatin and I KNOW I got a 25% increase in 30 days with 20 mg. Lipitor.
Other than that a good read.
Hey guy, you're a good researcher. Can you see what you can dig up as to the link between statins and myalgia. Not the incidence, but rather the CAUSATIVE rationale. I think it's real and simply cannot find what it is about the reduction of cholesterol (or the mevalonate precurser) that HURTS. Can it have to do with alternate chemicals that are produced INSTEAD of the normal pathways. Or does the statin inhibit OTHER enzymes than just the Hmg_CoA. Enzymes perhaps that the muscles need for proper functioning?
Perhaps, I'll never know?
(Proximate reason for this is reawakened concern is that my one weeek without Lipitor trial has decreased the pain in my shoulder- I THINK!:D:D...and I haven't taken a SINGLE placebo:D:D)
More on that later.