Just me again, Dorri. At the top of the page use the Search feature here and search on Preos. There are two "hits" particularly that should be of interest to you. One is titled "Osteoporosis - new drugs" and the other is titled "Areida or Zometa" (Aredia is the brand name for pamidronate). You should find some good reading pertaining to your various questions in these threads and posts.