I found your post very interesting. Two yrs ago I started fosamax and broke out in hives. Two specialists told me I was mistaken. I recently started actonel and developed a hideous rash with blisters on inner elbow. I believe it was the actonel. I have taken mtx, arava and many other things with no side effects. I have taken enbrel for 2 yrs. and have no side effects and it is helping the RA enormously. I am very reasonable and try to trust my doctors. I now take only enbrel and calcium and sit in the sun for 10 minutes a day for vit. D. It wouldnt surprise me that osteoporosis drugs are the next things pulled off the market.