28th July 2005
Hey blasterboy
How are you? I am affraid I might have to give you some bad news. Amitriptyline is a tricyclic anti-depressant which is also anti-cholinergic. This pill works for pain too, because it changes the way nerve endings work. It interferes with the way the nerves should work normally. People with GERD should not take this drug, because what it does is that it has anti-cholinergic effects which will decrease the LES pressure. People who have GERD should stay away from certain medications, and tricyclic-antidepressants and anti-cholinergic drugs are two of these meds. Amitriptyline has strong anti-cholinergic effects. This is how I developed a loose LES which right now I have GERD. I broke up with my girlfriend after 6 years and had some anxiety. The stupid doctor mis-diagnosed me as having depression even though I told him I have anxiety and not depression (I am in the medical field myself, so I know a lot about pills and medical conditions). But he insisted that I take the anti-depressants and finally I gave up and did. After 2 months of usage the pills made my lower sphincter so weak that everytime I eat now, I have reflux (I have LPR). I stopped taking the pill when I developed reflux but it is too late. The loose LES is obviously won't go back to normal because what the pill did was it reduced the LES pressure which results in the tone of the sphincter being reduced since the sphincter is just like a muscle and if it doesn't get used it will get weak. You can search this on the internet and find out about it if you like. I took 50mg once a day (at bedtime) for 2 months and that is all it took for this pill to decrease the LES pressure. I never ever had any problems with reflux, I could eat whatever I wanted to and now, because of this mistake I am not sure what I am going to do. So research about this pill because you definitely wouldn't want to be back where you were before. Take care. Mike
How are you? I am affraid I might have to give you some bad news. Amitriptyline is a tricyclic anti-depressant which is also anti-cholinergic. This pill works for pain too, because it changes the way nerve endings work. It interferes with the way the nerves should work normally. People with GERD should not take this drug, because what it does is that it has anti-cholinergic effects which will decrease the LES pressure. People who have GERD should stay away from certain medications, and tricyclic-antidepressants and anti-cholinergic drugs are two of these meds. Amitriptyline has strong anti-cholinergic effects. This is how I developed a loose LES which right now I have GERD. I broke up with my girlfriend after 6 years and had some anxiety. The stupid doctor mis-diagnosed me as having depression even though I told him I have anxiety and not depression (I am in the medical field myself, so I know a lot about pills and medical conditions). But he insisted that I take the anti-depressants and finally I gave up and did. After 2 months of usage the pills made my lower sphincter so weak that everytime I eat now, I have reflux (I have LPR). I stopped taking the pill when I developed reflux but it is too late. The loose LES is obviously won't go back to normal because what the pill did was it reduced the LES pressure which results in the tone of the sphincter being reduced since the sphincter is just like a muscle and if it doesn't get used it will get weak. You can search this on the internet and find out about it if you like. I took 50mg once a day (at bedtime) for 2 months and that is all it took for this pill to decrease the LES pressure. I never ever had any problems with reflux, I could eat whatever I wanted to and now, because of this mistake I am not sure what I am going to do. So research about this pill because you definitely wouldn't want to be back where you were before. Take care. Mike