I have migraines all month long but they tend to get worse as my period gets closer. I am 39 and perimenopausal. I've tried all the drugs also, watched eating "trigger" food and even went without medication. I also take axert and i've tried amerge. Both meds work great with very little side effects and quick relief. I recently started taking a natural product called Brevail. You can find information online at www.brevail.com. It's actually for breast health but has been found to cut down on headaches and migraines associated with periods. I have noticed that I don't have as many headaches throughout the month but as I said, as my period draws closer the headaches get worse. If you find something that works, please let us know :) . Thanks!