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   How many pill are too much (Diabetes board)

4th December 2007
My endocrinologist wants to add more pills to my routine. I am taking actos and janumet (combo of januvia & metformin)

HA1C is now 7.2 after adding janumet. How discouraging being that it was 6.8 before the janumet, but I did go off amaryl because I landed in the hospital with hypoglycemia

She suggests starlix or prandin. Still reading up on all the meds.

I am so tired of all the pills. Is insulin the answer? Not insulin resistant after having Cpeptide test.
6th December 2007
The C-peptide test does not, as far as I know, measure for insulin resistance but rather measure to see if you are producing any insulin.

In type 2 diabetes, there is usually a combination of insulin resistance plus some reduced insulin production. Both of these factors can vary greatly from person to person. Catherine is absolutely correct that the longer you have T2, the more progressive it is in terms of reduced insulin production.

Having said that, however, if you stopped taking the amaryl because of hypoglycemic events, you may not want to start on insulin just yet. Hypoglycemic events are not at all uncommon when taking insulin. I suspect that's why your doctor is trying to manage this with oral medication, rather than putting you on insulin. I would also recommend that if you go on insulin or back on the amaryl, that you test more often so that you can determine what causes the hypoglycemia (increased exercise? less food? stress?) Once you get a handle on that, it becomes easier to avoid extreme hypos and you'll learn the symptoms and test earlier, when you can treat it yourself with some sort of sugar (fruit juice, glucose tabs, hard candies, etc.) BEFORE it gets so low that you need to be hospitalized.

Whatever you do, you need to get your A1c back down. 7.2 isn't exactly TERRIBLE, but it's not terrific either.

Ruth
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