80 year old female w/ history of hypertension, type II diabetes, glaucoma
- eye pressure shot-up from mid to upper 20's to 40's in just a few days
in July 2007 - two ophthalmologists and one optometrist are perplexed
as to why

Currently using following drops for glaucoma:
1) Azopt - 2 drops/day - used for several months
2) Travatan - 1 drop/day - used for several months
3) Alphagan - 2 drops/day - started Oct. 25, 2007
4) Timolol - 2 drops/day - started Oct. 31, 2007

Started using the following drops over 12 years ago:
1) Timolol - Early 1990's - caused to test positive for Lupus -
problems with inflammation in knee
2) Xalatan - discontinued b/c patient heard about possibility of
changing eye color
3) Alphagan - used next

Also, use the following drugs:
1) Novolog 70/30 - insulin - 20 mg 2/day - started June 2007
2) Byetta - for diabetes - started around 1st of Sept 2007 -
discontinued 6 weeks later per physicians order b/c he thought
it might be the reason for the sudden increase of eye
pressure - However, after 3 weeks of discontinued use the eye
pressure remained out of control
3) Cozarr - for Blood pressure - 50 mg/day - taken for years
4) Coreg - for BP - 10 mg/day - taken about 5 or 6 months
5) Aldactone - taken to control enzyme in kidneys - 25 mg/day -
taken for years
6) Lasix - fluid - 20 mg/day - taken for years
7) Glucophage - diabetes - 500 mg/day starting 2 months ago (causes
diarrhea) - was taking 1000 mg/day

Also taking lipoflavonoid (vit B) for ringing in ears

Note: I found on Internet that Glucophage taken with water pills can
cause hyperglycemia.
Even though the medical experts that I have spoken with disagree,
it is suspicious that the eye pressure suddenly raised one month
after starting Novolog. Any thoughts/suggestions are appreciated.

I am a 62 year old female that has glaucoma and type II diabetes. About 4 months ago I started using the 5 level Byetta once a day and one month later I was switched to 10 level Byetta before breakfast and before dinner. My glaucome has been controlled a number of years by the use of alphagan and luminagan once each day with the pressures between 13 and 15 when they were checked every three months. My first glaucoma check after I began using Byetta, my pressures had increased to 17 and 19. My eye doctor changed my drops and after one month rechecked the pressures and they were at 24 in each eye. I go back after one week this time to see if the additional changes he has made have had any impact on the pressures.

The addition of the Byetta is the only change to my medication in over a year and during that time my pressures remained in the 13 to 15 range.

Has anyone other than the 80 year old person had the same reaction? I would like to take any responses to my doctor on Thursday.