I, too, noticed that after switching to Aciphex, I have become extremely constipated. I exercise regularly, am not overweight, eat healthy, consume a lot of fiber-rich foods and drink a lot of fluids; but I just realized this problem began soon after taking the Aciphex.

It does the best of the three PPIs I have tried for LPR symptoms, but I have gained a few pounds since starting the Aciphex, too. Depressing.

I'd love to stop taking these meds, but am also worried about the rebound effect I have heard that others have experienced.

I have taken the aciphex before and have not personally had any luck with it or many other drugs for my syptoms. In the last year I have been taking Prevacid, and haven't had a problem since. As long as I take it every morning I feel great, no heartburn, and I have had serious gerd and other intestinal issues for the last sixteen years. This is the most relief I've had in a long time, but the problem is it never seems to heal. If a miss a dose I get very sick and my stomach swells. I wish I could find a more long term fix. The doctors don't seem to know what to do for it besides the prescription med I'm taking.