Sorry to say, but Tylenol (a brand of acetaminophen) is not an anti-inflammatory...it's just a plain old anti-pyretic (brings down fever) and analgesic (painkiller). Aspirin (ASA) and Motrin/Advil (ibuprofen) are both anti-inflammatories, but I don't know if a paste of either would work...if I were going to try it, ASA would be my choice, as it's acetylsalicylic acid, which is what the salicylic acid that's used in many acne remedies is derived from...but I really don't know if it would work.