12th October 2006
Brutus,
Accupril is an ACE inhibitor and Benicar is an angiotensin blocker. Their method of action is quite different.
Since ACE is a multifaceted enzyme that mediates many hormonal and prostaglandin type reactions I would expect VAST differences in side effects between the two classes of drugs.
Blocking ACE does far more than just lower BP and causing depression isn't completely out of the ordinary.
Besides, after taking an ACE inhibitor for several years there is usually a loss of effectiveness anyway...so the switch to an ARB sounds like a good idea.
Accupril is an ACE inhibitor and Benicar is an angiotensin blocker. Their method of action is quite different.
Since ACE is a multifaceted enzyme that mediates many hormonal and prostaglandin type reactions I would expect VAST differences in side effects between the two classes of drugs.
Blocking ACE does far more than just lower BP and causing depression isn't completely out of the ordinary.
Besides, after taking an ACE inhibitor for several years there is usually a loss of effectiveness anyway...so the switch to an ARB sounds like a good idea.